diff --git a/hadoop-tools/hadoop-aws/src/main/java/org/apache/hadoop/fs/s3a/S3AFileSystem.java b/hadoop-tools/hadoop-aws/src/main/java/org/apache/hadoop/fs/s3a/S3AFileSystem.java
index 4424ebaa5ef..eb65cfa6d1f 100644
--- a/hadoop-tools/hadoop-aws/src/main/java/org/apache/hadoop/fs/s3a/S3AFileSystem.java
+++ b/hadoop-tools/hadoop-aws/src/main/java/org/apache/hadoop/fs/s3a/S3AFileSystem.java
@@ -1572,6 +1572,7 @@ UploadPartResult uploadPart(UploadPartRequest request)
     long len = request.getPartSize();
     incrementPutStartStatistics(len);
     try {
+      setOptionalUploadPartRequestParameters(request);
       UploadPartResult uploadPartResult = s3.uploadPart(request);
       incrementPutCompletedStatistics(true, len);
       return uploadPartResult;
@@ -2563,6 +2564,23 @@ protected void setOptionalMultipartUploadRequestParameters(
     }
   }
 
+  /**
+   * Sets server side encryption parameters to the part upload
+   * request when encryption is enabled.
+   * @param request upload part request
+   */
+  protected void setOptionalUploadPartRequestParameters(
+      UploadPartRequest request) {
+    switch (serverSideEncryptionAlgorithm) {
+    case SSE_C:
+      if (isNotBlank(getServerSideEncryptionKey(bucket, getConf()))) {
+        request.setSSECustomerKey(generateSSECustomerKey());
+      }
+      break;
+    default:
+    }
+  }
+
   /**
    * Initiate a multipart upload from the preconfigured request.
    * Retry policy: none + untranslated.
diff --git a/hadoop-tools/hadoop-aws/src/test/java/org/apache/hadoop/fs/s3a/MockS3AFileSystem.java b/hadoop-tools/hadoop-aws/src/test/java/org/apache/hadoop/fs/s3a/MockS3AFileSystem.java
index 49525802a9c..1062a120779 100644
--- a/hadoop-tools/hadoop-aws/src/test/java/org/apache/hadoop/fs/s3a/MockS3AFileSystem.java
+++ b/hadoop-tools/hadoop-aws/src/test/java/org/apache/hadoop/fs/s3a/MockS3AFileSystem.java
@@ -24,6 +24,7 @@
 import com.amazonaws.AmazonClientException;
 import com.amazonaws.services.s3.AmazonS3;
 import com.amazonaws.services.s3.model.InitiateMultipartUploadRequest;
+import com.amazonaws.services.s3.model.UploadPartRequest;
 import org.slf4j.Logger;
 import org.slf4j.LoggerFactory;
 
@@ -277,6 +278,11 @@ protected void setOptionalMultipartUploadRequestParameters(
 // no-op
   }
 
+  @Override
+  protected void setOptionalUploadPartRequestParameters(
+      UploadPartRequest request) {
+  }
+
   @Override
   @SuppressWarnings("deprecation")
   public long getDefaultBlockSize() {
diff --git a/hadoop-tools/hadoop-aws/src/test/java/org/apache/hadoop/fs/s3a/scale/ITestS3AHugeFilesSSECDiskBlocks.java b/hadoop-tools/hadoop-aws/src/test/java/org/apache/hadoop/fs/s3a/scale/ITestS3AHugeFilesSSECDiskBlocks.java
new file mode 100644
index 00000000000..2e5185bf55d
--- /dev/null
+++ b/hadoop-tools/hadoop-aws/src/test/java/org/apache/hadoop/fs/s3a/scale/ITestS3AHugeFilesSSECDiskBlocks.java
@@ -0,0 +1,58 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one
+ * or more contributor license agreements.  See the NOTICE file
+ * distributed with this work for additional information
+ * regarding copyright ownership.  The ASF licenses this file
+ * to you under the Apache License, Version 2.0 (the
+ * "License"); you may not use this file except in compliance
+ * with the License.  You may obtain a copy of the License at
+ * <p>
+ * http://www.apache.org/licenses/LICENSE-2.0
+ * <p>
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+*/
+
+package org.apache.hadoop.fs.s3a.scale;
+
+import org.apache.hadoop.conf.Configuration;
+import org.apache.hadoop.fs.s3a.Constants;
+import org.apache.hadoop.fs.s3a.S3AEncryptionMethods;
+import org.apache.hadoop.fs.s3a.S3ATestUtils;
+
+import static org.apache.hadoop.fs.s3a.S3ATestUtils.skipIfEncryptionTestsDisabled;
+
+/**
+ * Concrete class that extends {@link ITestS3AHugeFilesDiskBlocks}
+ * and tests huge files operations with SSE-C encryption enabled.
+ * Skipped if the SSE tests are disabled.
+ */
+public class ITestS3AHugeFilesSSECDiskBlocks
+    extends ITestS3AHugeFilesDiskBlocks {
+
+  private static final String KEY_1
+      = "4niV/jPK5VFRHY+KNb6wtqYd4xXyMgdJ9XQJpcQUVbs=";
+
+  @Override
+  public void setup() throws Exception {
+    super.setup();
+    skipIfEncryptionTestsDisabled(getConfiguration());
+  }
+
+  @Override
+  protected Configuration createScaleConfiguration() {
+    Configuration conf = super.createScaleConfiguration();
+    S3ATestUtils.disableFilesystemCaching(conf);
+    conf.set(Constants.SERVER_SIDE_ENCRYPTION_ALGORITHM,
+        getSSEAlgorithm().getMethod());
+    conf.set(Constants.SERVER_SIDE_ENCRYPTION_KEY, KEY_1);
+    return conf;
+  }
+
+  private S3AEncryptionMethods getSSEAlgorithm() {
+    return S3AEncryptionMethods.SSE_C;
+  }
+}