diff --git a/httpclient5/src/main/java/org/apache/hc/client5/http/impl/DefaultHttpRequestRetryStrategy.java b/httpclient5/src/main/java/org/apache/hc/client5/http/impl/DefaultHttpRequestRetryStrategy.java
index 2f8695af7..b1be581ca 100644
--- a/httpclient5/src/main/java/org/apache/hc/client5/http/impl/DefaultHttpRequestRetryStrategy.java
+++ b/httpclient5/src/main/java/org/apache/hc/client5/http/impl/DefaultHttpRequestRetryStrategy.java
@@ -30,6 +30,7 @@ package org.apache.hc.client5.http.impl;
 import java.io.IOException;
 import java.io.InterruptedIOException;
 import java.net.ConnectException;
+import java.net.NoRouteToHostException;
 import java.net.UnknownHostException;
 import java.util.Arrays;
 import java.util.Collection;
@@ -106,6 +107,7 @@ public class DefaultHttpRequestRetryStrategy implements HttpRequestRetryStrategy
      * <li>UnknownHostException</li>
      * <li>ConnectException</li>
      * <li>ConnectionClosedException</li>
+     * <li>NoRouteToHostException</li>
      * <li>SSLException</li>
      * </ul>
      *
@@ -129,6 +131,7 @@ public class DefaultHttpRequestRetryStrategy implements HttpRequestRetryStrategy
                         UnknownHostException.class,
                         ConnectException.class,
                         ConnectionClosedException.class,
+                        NoRouteToHostException.class,
                         SSLException.class),
                 Arrays.asList(
                         HttpStatus.SC_TOO_MANY_REQUESTS,
diff --git a/httpclient5/src/test/java/org/apache/hc/client5/http/impl/TestDefaultHttpRequestRetryStrategy.java b/httpclient5/src/test/java/org/apache/hc/client5/http/impl/TestDefaultHttpRequestRetryStrategy.java
index 0411326e4..fc8c575dd 100644
--- a/httpclient5/src/test/java/org/apache/hc/client5/http/impl/TestDefaultHttpRequestRetryStrategy.java
+++ b/httpclient5/src/test/java/org/apache/hc/client5/http/impl/TestDefaultHttpRequestRetryStrategy.java
@@ -28,6 +28,7 @@ package org.apache.hc.client5.http.impl;
 
 import java.io.IOException;
 import java.net.ConnectException;
+import java.net.NoRouteToHostException;
 import java.net.SocketTimeoutException;
 import java.net.UnknownHostException;
 import java.util.Date;
@@ -126,6 +127,13 @@ public class TestDefaultHttpRequestRetryStrategy {
         Assert.assertFalse(retryStrategy.retryRequest(request, new ConnectionClosedException(), 1, null));
     }
 
+    @Test
+    public void noRetryForNoRouteToHostException() {
+        final HttpGet request = new HttpGet("/");
+
+        Assert.assertFalse(retryStrategy.retryRequest(request, new NoRouteToHostException(), 1, null));
+    }
+
     @Test
     public void noRetryOnSSLFailure() throws Exception {
         final HttpGet request = new HttpGet("/");