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<title>Evolutionary trees from DNA sequences: a maximum ... [J Mol Evol. 1981] - PubMed - NCBI</title>
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">Primer-BLAST</a></li><li><a href="/sutils/static/prosplign/prosplign.html" title=" Tool for aligning proteins to genomic DNA ">ProSplign</a></li><li><a href="http://pubchem.ncbi.nlm.nih.gov/search/search.cgi" title=" Searches PubChem Compound by chemical structure ">PubChem Structure Search</a></li><li><a href="http://www.ncbi.nlm.nih.gov/projects/SNP/" title=" The SNP database tools page provides links to the general submission guidelines and to the submission handle request. 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<div class="rprt_all"><div class="rprt abstract"><div class="cit"><a href="#" title="Journal of molecular evolution." abstractLink="yes" alsec="jour" alterm="J Mol Evol.">J Mol Evol.</a> 1981;17(6):368-76.</div><h1>Evolutionary trees from DNA sequences: a maximum likelihood approach.</h1><div class="auths"><a href="/pubmed?term=Felsenstein%20J%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=7288891">Felsenstein J</a>.</div><div class="abstr"><h3>Abstract</h3><div class=""><p>The application of maximum likelihood techniques to the estimation of evolutionary trees from nucleic acid sequence data is discussed. A computationally feasible method for finding such maximum likelihood estimates is developed, and a computer program is available. This method has advantages over the traditional parsimony algorithms, which can give misleading results if rates of evolution differ in different lineages. It also allows the testing of hypotheses about the constancy of evolutionary rates by likelihood ratio tests, and gives rough indication of the error of ;the estimate of the tree.</p></div></div><div class="aux"><div class="resc"><dl class="rprtid"><dt>PMID:</dt> <dd>7288891</dd> <dd> [PubMed - indexed for MEDLINE] </dd><dd> </dd></dl></div><div class="links"></div></div><div class="morecit"><h3><a title="Supplemental information" class="jig-ncbitoggler ui-ncbitoggler" href="#"><span class="ui-ncbitoggler-master-text">Publication Types, MeSH Terms, Substances</span><span class="ui-icon ui-icon-triangle-1-e"></span></a></h3><div class="ui-ncbi-toggler-slave"><h4>Publication Types</h4><ul><li><a href="#" abstractLink="yes" alsec="ptyp" alterm="Research Support, U.S. Gov't, Non-P.H.S.">Research Support, U.S. Gov't, Non-P.H.S.</a></li></ul><h4>MeSH Terms</h4><ul><li><a href="#" abstractLink="yes" alsec="mesh" alterm="Base Sequence*">Base Sequence*</a></li><li><a href="#" abstractLink="yes" alsec="mesh" alterm="Biological Evolution*">Biological Evolution*</a></li><li><a href="#" abstractLink="yes" alsec="mesh" alterm="Computers">Computers</a></li><li><a href="#" abstractLink="yes" alsec="mesh" alterm="DNA/genetics*">DNA/genetics*</a></li><li><a href="#" abstractLink="yes" alsec="mesh" alterm="Mathematics">Mathematics</a></li><li><a href="#" abstractLink="yes" alsec="mesh" alterm="Models, Biological">Models, Biological</a></li><li><a href="#" abstractLink="yes" alsec="mesh" alterm="Phylogeny">Phylogeny</a></li></ul><h4>Substances</h4><ul><li><a href="#" abstractLink="yes" alsec="subs" alterm="DNA">DNA</a></li></ul></div></div><div class="morecit"><h3><a title="Links to resources such as full text articles and biological data" class="jig-ncbitoggler ui-ncbitoggler" href="#"><span class="ui-ncbitoggler-master-text">LinkOut - more resources</span><span class="ui-icon ui-icon-triangle-1-e"></span></a></h3><div class="ui-ncbi-toggler-slave"><div class="linkoutlist"><h4>Other Literature Sources</h4><ul><li><a title="Free resource" href="http://www.scholaruniverse.com/ncbi-linkout?id=7288891" ref="itool=Abstract&amp;PrId=3087&amp;uid=7288891&amp;db=pubmed&amp;log$=linkoutlink&amp;nlmid=0360051" target="_blank">COS Scholar Universe</a></li></ul></div></div></div><div id="comments_panel" data-recid="7288891" data-exp="true" data-rsys="1"><div id="comments_panel_head"><a id="coments_panel_anchor" href="/pubmedcommons/" name="comments">PubMed Commons home</a><h2><span id="show_comments" title="Shows comments">
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