diff --git a/jetty-http2/http2-http-client-transport/src/main/java/org/eclipse/jetty/http2/client/http/HttpReceiverOverHTTP2.java b/jetty-http2/http2-http-client-transport/src/main/java/org/eclipse/jetty/http2/client/http/HttpReceiverOverHTTP2.java
index 30ccfc75de9..ca85a6e1d15 100644
--- a/jetty-http2/http2-http-client-transport/src/main/java/org/eclipse/jetty/http2/client/http/HttpReceiverOverHTTP2.java
+++ b/jetty-http2/http2-http-client-transport/src/main/java/org/eclipse/jetty/http2/client/http/HttpReceiverOverHTTP2.java
@@ -20,7 +20,9 @@ package org.eclipse.jetty.http2.client.http;
 
 import java.io.IOException;
 import java.nio.ByteBuffer;
+import java.util.ArrayDeque;
 import java.util.Locale;
+import java.util.Queue;
 
 import org.eclipse.jetty.client.HttpChannel;
 import org.eclipse.jetty.client.HttpExchange;
@@ -38,10 +40,12 @@ import org.eclipse.jetty.http2.frames.ResetFrame;
 import org.eclipse.jetty.io.ByteBufferPool;
 import org.eclipse.jetty.util.BufferUtil;
 import org.eclipse.jetty.util.Callback;
-import org.eclipse.jetty.util.CompletableCallback;
+import org.eclipse.jetty.util.IteratingCallback;
 
 public class HttpReceiverOverHTTP2 extends HttpReceiver implements Stream.Listener
 {
+    private final ContentNotifier contentNotifier = new ContentNotifier();
+
     public HttpReceiverOverHTTP2(HttpChannel channel)
     {
         super(channel);
@@ -111,40 +115,8 @@ public class HttpReceiverOverHTTP2 extends HttpReceiver implements Stream.Listen
         copy.put(original);
         BufferUtil.flipToFlush(copy, 0);
 
-        CompletableCallback delegate = new CompletableCallback()
-        {
-            @Override
-            public void succeeded()
-            {
-                byteBufferPool.release(copy);
-                callback.succeeded();
-                super.succeeded();
-            }
-
-            @Override
-            public void failed(Throwable x)
-            {
-                byteBufferPool.release(copy);
-                callback.failed(x);
-                super.failed(x);
-            }
-
-            @Override
-            public void resume()
-            {
-                if (frame.isEndStream())
-                    responseSuccess(exchange);
-            }
-
-            @Override
-            public void abort(Throwable failure)
-            {
-            }
-        };
-
-        responseContent(exchange, copy, delegate);
-        if (!delegate.tryComplete())
-            delegate.resume();
+        contentNotifier.offer(new DataInfo(exchange, copy, callback, frame.isEndStream()));
+        contentNotifier.iterate();
     }
 
     @Override
@@ -164,4 +136,70 @@ public class HttpReceiverOverHTTP2 extends HttpReceiver implements Stream.Listen
     {
         responseFailure(failure);
     }
+
+    private class ContentNotifier extends IteratingCallback
+    {
+        private final Queue<DataInfo> queue = new ArrayDeque<>();
+        private DataInfo dataInfo;
+
+        private boolean offer(DataInfo dataInfo)
+        {
+            synchronized (this)
+            {
+                return queue.offer(dataInfo);
+            }
+        }
+
+        @Override
+        protected Action process() throws Exception
+        {
+            DataInfo dataInfo;
+            synchronized (this)
+            {
+                dataInfo = queue.poll();
+            }
+            if (dataInfo == null)
+                return Action.IDLE;
+
+            this.dataInfo = dataInfo;
+            responseContent(dataInfo.exchange, dataInfo.buffer, this);
+            return Action.SCHEDULED;
+        }
+
+        @Override
+        public void succeeded()
+        {
+            ByteBufferPool byteBufferPool = getHttpDestination().getHttpClient().getByteBufferPool();
+            byteBufferPool.release(dataInfo.buffer);
+            dataInfo.callback.succeeded();
+            if (dataInfo.last)
+                responseSuccess(dataInfo.exchange);
+            super.succeeded();
+        }
+
+        @Override
+        protected void onCompleteFailure(Throwable failure)
+        {
+            ByteBufferPool byteBufferPool = getHttpDestination().getHttpClient().getByteBufferPool();
+            byteBufferPool.release(dataInfo.buffer);
+            dataInfo.callback.failed(failure);
+            responseFailure(failure);
+        }
+    }
+
+    private static class DataInfo
+    {
+        private final HttpExchange exchange;
+        private final ByteBuffer buffer;
+        private final Callback callback;
+        private final boolean last;
+
+        private DataInfo(HttpExchange exchange, ByteBuffer buffer, Callback callback, boolean last)
+        {
+            this.exchange = exchange;
+            this.buffer = buffer;
+            this.callback = callback;
+            this.last = last;
+        }
+    }
 }
diff --git a/tests/test-http-client-transport/src/test/java/org/eclipse/jetty/http/client/HttpClientTest.java b/tests/test-http-client-transport/src/test/java/org/eclipse/jetty/http/client/HttpClientTest.java
index dcfdde77b54..5567ed81f7d 100644
--- a/tests/test-http-client-transport/src/test/java/org/eclipse/jetty/http/client/HttpClientTest.java
+++ b/tests/test-http-client-transport/src/test/java/org/eclipse/jetty/http/client/HttpClientTest.java
@@ -26,6 +26,8 @@ import java.util.Random;
 import java.util.concurrent.CountDownLatch;
 import java.util.concurrent.ExecutionException;
 import java.util.concurrent.TimeUnit;
+import java.util.concurrent.atomic.AtomicInteger;
+import java.util.concurrent.atomic.AtomicReference;
 import java.util.stream.IntStream;
 
 import javax.servlet.ServletException;
@@ -44,6 +46,7 @@ import org.eclipse.jetty.http.HttpStatus;
 import org.eclipse.jetty.http2.FlowControlStrategy;
 import org.eclipse.jetty.server.Request;
 import org.eclipse.jetty.server.handler.AbstractHandler;
+import org.eclipse.jetty.util.Callback;
 import org.eclipse.jetty.util.IO;
 import org.eclipse.jetty.util.ssl.SslContextFactory;
 import org.eclipse.jetty.util.thread.QueuedThreadPool;
@@ -442,6 +445,49 @@ public class HttpClientTest extends AbstractTest
         Assert.assertTrue(closeLatch.await(1, TimeUnit.SECONDS));
     }
 
+    @Test
+    public void testAsyncResponseContentBackPressure() throws Exception
+    {
+        start(new AbstractHandler()
+        {
+            @Override
+            public void handle(String target, Request baseRequest, HttpServletRequest request, HttpServletResponse response) throws IOException, ServletException
+            {
+                baseRequest.setHandled(true);
+                // Large write to generate multiple DATA frames.
+                response.getOutputStream().write(new byte[256 * 1024]);
+            }
+        });
+
+        CountDownLatch completeLatch = new CountDownLatch(1);
+        AtomicInteger counter = new AtomicInteger();
+        AtomicReference<Callback> callbackRef = new AtomicReference<>();
+        AtomicReference<CountDownLatch> latchRef = new AtomicReference<>(new CountDownLatch(1));
+        client.newRequest("localhost", connector.getLocalPort())
+                .scheme(getScheme())
+                .onResponseContentAsync((response, content, callback) ->
+                {
+                    if (counter.incrementAndGet() == 1)
+                    {
+                        callbackRef.set(callback);
+                        latchRef.get().countDown();
+                    }
+                    else
+                    {
+                        callback.succeeded();
+                    }
+                })
+                .send(result -> completeLatch.countDown());
+
+        Assert.assertTrue(latchRef.get().await(5, TimeUnit.SECONDS));
+        // Wait some time to verify that back pressure is applied correctly.
+        Thread.sleep(1000);
+        Assert.assertEquals(1, counter.get());
+        callbackRef.get().succeeded();
+
+        Assert.assertTrue(completeLatch.await(5, TimeUnit.SECONDS));
+    }
+
     private void sleep(long time) throws IOException
     {
         try