diff --git a/wp-includes/class-wp-theme-json.php b/wp-includes/class-wp-theme-json.php
index f4442471e1..b929c95608 100644
--- a/wp-includes/class-wp-theme-json.php
+++ b/wp-includes/class-wp-theme-json.php
@@ -2493,7 +2493,7 @@ class WP_Theme_JSON {
 			// The above rule is negated for alignfull children of nested containers.
 			$css .= '.has-global-padding :where(.has-global-padding) > .alignfull { margin-right: 0; margin-left: 0; }';
 			// Some of the children of alignfull blocks without content width should also get padding: text blocks and non-alignfull container blocks.
-			$css .= '.has-global-padding > .alignfull:where(:not(.has-global-padding)) > :where([class*="wp-block-"]:not(.alignfull):not([class*="__"]),p,h1,h2,h3,h4,h5,h6,ul,ol) { padding-right: var(--wp--style--root--padding-right); padding-left: var(--wp--style--root--padding-left); }';
+			$css .= '.has-global-padding > .alignfull:where(:not(.has-global-padding):not(.is-layout-flex):not(.is-layout-grid)) > :where([class*="wp-block-"]:not(.alignfull):not([class*="__"]),p,h1,h2,h3,h4,h5,h6,ul,ol) { padding-right: var(--wp--style--root--padding-right); padding-left: var(--wp--style--root--padding-left); }';
 			// The above rule also has to be negated for blocks inside nested `.has-global-padding` blocks.
 			$css .= '.has-global-padding :where(.has-global-padding) > .alignfull:where(:not(.has-global-padding)) > :where([class*="wp-block-"]:not(.alignfull):not([class*="__"]),p,h1,h2,h3,h4,h5,h6,ul,ol) { padding-right: 0; padding-left: 0; }';
 		}
diff --git a/wp-includes/version.php b/wp-includes/version.php
index 3d24c8f562..bb2184d96f 100644
--- a/wp-includes/version.php
+++ b/wp-includes/version.php
@@ -16,7 +16,7 @@
  *
  * @global string $wp_version
  */
-$wp_version = '6.4-alpha-56545';
+$wp_version = '6.4-alpha-56546';
 
 /**
  * Holds the WordPress DB revision, increments when changes are made to the WordPress DB schema.