diff --git a/hapi-fhir-validation/src/test/java/org/hl7/fhir/dstu3/hapi/validation/FhirInstanceValidatorDstu3Test.java b/hapi-fhir-validation/src/test/java/org/hl7/fhir/dstu3/hapi/validation/FhirInstanceValidatorDstu3Test.java
index 4fd43865736..32295577991 100644
--- a/hapi-fhir-validation/src/test/java/org/hl7/fhir/dstu3/hapi/validation/FhirInstanceValidatorDstu3Test.java
+++ b/hapi-fhir-validation/src/test/java/org/hl7/fhir/dstu3/hapi/validation/FhirInstanceValidatorDstu3Test.java
@@ -336,6 +336,19 @@ public class FhirInstanceValidatorDstu3Test {
 		assertTrue(output.isSuccessful());
 	}
 
+	/**
+	 * See #739
+	 */
+	@Test
+	public void testValidateMedicationIngredient() throws IOException {
+		String input = IOUtils.toString(FhirInstanceValidatorDstu3Test.class.getResourceAsStream("/dstu3/bug739.json"), Charsets.UTF_8);
+
+		ValidationResult results = myVal.validateWithResult(input);
+		List<SingleValidationMessage> outcome = logResultsAndReturnNonInformationalOnes(results);
+		assertThat(outcome.toString(), containsString("Element 'Medication.ingredient.item[x]': minimum required = 1"));
+
+	}
+
 	@Test
 	public void testValidateQuestionnaireResponse() throws IOException {
 		String input = IOUtils.toString(FhirInstanceValidatorDstu3Test.class.getResourceAsStream("/qr_jon.xml"));
diff --git a/hapi-fhir-validation/src/test/resources/dstu3/bug739.json b/hapi-fhir-validation/src/test/resources/dstu3/bug739.json
new file mode 100644
index 00000000000..b1b34196c57
--- /dev/null
+++ b/hapi-fhir-validation/src/test/resources/dstu3/bug739.json
@@ -0,0 +1,45 @@
+{
+	"resourceType": "Medication",
+	"code": {
+		"coding": [
+			{
+				"system": "urn:2.16.840.1.113883.6.88",
+				"code": "1191",
+				"display": "aspirin"
+			}
+		],
+		"text": "ASPIRIN 325 MG TABLET"
+	},
+	"form": {
+		"coding": [
+			{
+				"system": "http://upmc.com/enterprises/rakia/rakida/cerner/h1/medication/form/code",
+				"code": "687545",
+				"display": "Tab"
+			}
+		],
+		"text": "Tab"
+	},
+	"ingredient": [
+		{
+			"item": {
+				"reference": "medication/613168",
+				"display": "aspirin"
+			},
+			"amount": {
+				"numerator": {
+					"value": "650",
+					"unit": "mg",
+					"system": "http://upmc.com/enterprises/rakia/rakida/cerner/h1/medication/strength/unit",
+					"code": "MG"
+				},
+				"denominator": {
+					"value": "2",
+					"unit": "tab(s)",
+					"system": "http://upmc.com/enterprises/rakia/rakida/cerner/h1/medication/volume/unit",
+					"code": "TAB"
+				}
+			}
+		}
+	]
+}