diff --git a/hapi-fhir-jpaserver-base/src/main/java/ca/uhn/fhir/jpa/dao/SearchBuilder.java b/hapi-fhir-jpaserver-base/src/main/java/ca/uhn/fhir/jpa/dao/SearchBuilder.java
index 7de8452ee3b..a2badff5ed0 100644
--- a/hapi-fhir-jpaserver-base/src/main/java/ca/uhn/fhir/jpa/dao/SearchBuilder.java
+++ b/hapi-fhir-jpaserver-base/src/main/java/ca/uhn/fhir/jpa/dao/SearchBuilder.java
@@ -76,13 +76,6 @@ import ca.uhn.fhir.context.RuntimeChildChoiceDefinition;
 import ca.uhn.fhir.context.RuntimeChildResourceDefinition;
 import ca.uhn.fhir.context.RuntimeResourceDefinition;
 import ca.uhn.fhir.context.RuntimeSearchParam;
-import ca.uhn.fhir.jpa.dao.BaseHapiFhirDao;
-import ca.uhn.fhir.jpa.dao.BaseHapiFhirResourceDao;
-import ca.uhn.fhir.jpa.dao.IDao;
-import ca.uhn.fhir.jpa.dao.IFhirResourceDao;
-import ca.uhn.fhir.jpa.dao.IFulltextSearchSvc;
-import ca.uhn.fhir.jpa.dao.ISearchBuilder;
-import ca.uhn.fhir.jpa.dao.ISearchParamRegistry;
 import ca.uhn.fhir.jpa.dao.data.IForcedIdDao;
 import ca.uhn.fhir.jpa.dao.data.IResourceIndexedSearchParamUriDao;
 import ca.uhn.fhir.jpa.entity.BaseHasResource;
@@ -1102,7 +1095,7 @@ public class SearchBuilder implements ISearchBuilder {
 		if (!isBlank(unitsValue)) {
 			code = theBuilder.equal(theFrom.get("myUnits"), unitsValue);
 		}
-
+		
 		cmpValue = ObjectUtils.defaultIfNull(cmpValue, ParamPrefixEnum.EQUAL);
 		final Expression<BigDecimal> path = theFrom.get("myValue");
 		String invalidMessageName = "invalidQuantityPrefix";
@@ -1768,6 +1761,39 @@ public class SearchBuilder implements ISearchBuilder {
 	}
 
 	private void searchForIdsWithAndOr(String theResourceName, String theParamName, List<List<? extends IQueryParameterType>> theAndOrParams) {
+		
+		for (int andListIdx = 0; andListIdx < theAndOrParams.size(); andListIdx++) {
+			List<? extends IQueryParameterType> nextOrList = theAndOrParams.get(andListIdx);
+			
+			for (int orListIdx = 0; orListIdx < nextOrList.size(); orListIdx++) {
+				IQueryParameterType nextOr = nextOrList.get(orListIdx);
+				boolean hasNoValue = false;
+				if (nextOr.getMissing() != null) {
+					continue;
+				}
+				if (nextOr instanceof QuantityParam) {
+					if (isBlank(((QuantityParam) nextOr).getValueAsString())) {
+						hasNoValue = true;
+					}
+				}
+				
+				if (hasNoValue) {
+					ourLog.debug("Ignoring empty parameter: {}", theParamName);
+					nextOrList.remove(orListIdx);
+					orListIdx--;
+				}
+			}
+			
+			if (nextOrList.isEmpty()) {
+				theAndOrParams.remove(andListIdx);
+				andListIdx--;
+			}
+		}
+
+		if (theAndOrParams.isEmpty()) {
+			return;
+		}
+		
 		if (theParamName.equals(BaseResource.SP_RES_ID)) {
 
 			addPredicateResourceId(theAndOrParams);
diff --git a/hapi-fhir-jpaserver-base/src/test/java/ca/uhn/fhir/jpa/provider/dstu3/ResourceProviderDstu3Test.java b/hapi-fhir-jpaserver-base/src/test/java/ca/uhn/fhir/jpa/provider/dstu3/ResourceProviderDstu3Test.java
index f7c721fa503..7d048e7f8c2 100644
--- a/hapi-fhir-jpaserver-base/src/test/java/ca/uhn/fhir/jpa/provider/dstu3/ResourceProviderDstu3Test.java
+++ b/hapi-fhir-jpaserver-base/src/test/java/ca/uhn/fhir/jpa/provider/dstu3/ResourceProviderDstu3Test.java
@@ -178,14 +178,41 @@ public class ResourceProviderDstu3Test extends BaseResourceProviderDstu3Test {
 		myDaoConfig.setAllowMultipleDelete(true);
 	}
 
-	
+	@Test
+	public void testSearchWithEmptyParameter() throws Exception {
+		Observation obs= new Observation();
+		obs.setStatus(ObservationStatus.FINAL);
+		obs.getCode().addCoding().setSystem("foo").setCode("bar");
+		ourClient.create().resource(obs).execute();
+		
+		testSearchWithEmptyParameter("/Observation?value-quantity=");
+		testSearchWithEmptyParameter("/Observation?code=bar&value-quantity=");
+		testSearchWithEmptyParameter("/Observation?value-date=");
+		testSearchWithEmptyParameter("/Observation?code=bar&value-date=");
+		testSearchWithEmptyParameter("/Observation?value-concept=");
+		testSearchWithEmptyParameter("/Observation?code=bar&value-concept=");
+	}
+
+	private void testSearchWithEmptyParameter(String url) throws IOException, ClientProtocolException {
+		HttpGet get = new HttpGet(ourServerBase + url);
+		CloseableHttpResponse resp = ourHttpClient.execute(get);
+		try {
+			assertEquals(200, resp.getStatusLine().getStatusCode());
+			String respString = IOUtils.toString(resp.getEntity().getContent(), Constants.CHARSET_UTF8);
+			Bundle bundle = myFhirCtx.newXmlParser().parseResource(Bundle.class, respString);
+			assertEquals(1, bundle.getEntry().size());
+		} finally {
+			IOUtils.closeQuietly(resp.getEntity().getContent());
+		}
+	}
+
 	@Test
 	public void testSearchWithMissingDate2() throws Exception {
 		MedicationRequest mr1 = new MedicationRequest();
 		mr1.getCategory().addCoding().setSystem("urn:medicationroute").setCode("oral");
 		mr1.addDosageInstruction().getTiming().addEventElement().setValueAsString("2017-01-01");
 		IIdType id1 = myMedicationRequestDao.create(mr1).getId().toUnqualifiedVersionless();
-		
+
 		MedicationRequest mr2 = new MedicationRequest();
 		mr2.getCategory().addCoding().setSystem("urn:medicationroute").setCode("oral");
 		IIdType id2 = myMedicationRequestDao.create(mr2).getId().toUnqualifiedVersionless();
@@ -195,38 +222,34 @@ public class ResourceProviderDstu3Test extends BaseResourceProviderDstu3Test {
 		try {
 			assertEquals(200, resp.getStatusLine().getStatusCode());
 			Bundle bundle = myFhirCtx.newXmlParser().parseResource(Bundle.class, IOUtils.toString(resp.getEntity().getContent(), Constants.CHARSET_UTF8));
-			
+
 			List<String> ids = toUnqualifiedVersionlessIdValues(bundle);
 			assertThat(ids, contains(id1.getValue()));
 		} finally {
 			IOUtils.closeQuietly(resp);
 		}
-		
 
-		
 	}
-	
+
 	@Test
 	public void testEverythingWithOnlyPatient() {
 		Patient p = new Patient();
 		p.setActive(true);
 		IIdType id = ourClient.create().resource(p).execute().getId().toUnqualifiedVersionless();
-		
+
 		myFhirCtx.getRestfulClientFactory().setSocketTimeout(300 * 1000);
-		
+
 		Bundle response = ourClient
-			.operation()
-			.onInstance(id)
-			.named("everything")
-			.withNoParameters(Parameters.class)
-			.returnResourceType(Bundle.class)
-			.execute();
-		
+				.operation()
+				.onInstance(id)
+				.named("everything")
+				.withNoParameters(Parameters.class)
+				.returnResourceType(Bundle.class)
+				.execute();
+
 		assertEquals(1, response.getEntry().size());
 	}
-	
 
-	
 	@Test
 	public void testSaveAndRetrieveResourceWithExtension() {
 		Patient nextPatient = new Patient();
@@ -239,7 +262,7 @@ public class ResourceProviderDstu3Test extends BaseResourceProviderDstu3Test {
 		ourClient.update().resource(nextPatient).execute();
 
 		Patient p = ourClient.read().resource(Patient.class).withId("B").execute();
-		
+
 		String encoded = myFhirCtx.newJsonParser().setPrettyPrint(true).encodeResourceToString(p);
 		ourLog.info(encoded);
 
diff --git a/src/changes/changes.xml b/src/changes/changes.xml
index 7dc713b157d..edf36e28bf2 100644
--- a/src/changes/changes.xml
+++ b/src/changes/changes.xml
@@ -24,6 +24,10 @@
 				looked like before the update. This change was made to support the change above, but
 				seems like a useful feature all around.
 			</action>
+			<action type="fix">
+				Fix HTTP 500 error in JPA server if a numeric search parameter was supplied with no value, e.g.
+				<![CDATA[<code>GET /Observation?value-quantity=</code>]]>
+			</action>
 		</release>
 		<release version="2.5" date="2017-06-08">
 			<action type="fix">