diff --git a/packages/compiler-cli/src/ngtsc/typecheck/src/type_check_block.ts b/packages/compiler-cli/src/ngtsc/typecheck/src/type_check_block.ts
index bb2ba89098..dbe40a0925 100644
--- a/packages/compiler-cli/src/ngtsc/typecheck/src/type_check_block.ts
+++ b/packages/compiler-cli/src/ngtsc/typecheck/src/type_check_block.ts
@@ -418,10 +418,10 @@ class TcbReferenceOp extends TcbOp {
 
   execute(): ts.Identifier {
     const id = this.tcb.allocateId();
-    let initializer = ts.getMutableClone(
+    let initializer =
         this.target instanceof TmplAstTemplate || this.target instanceof TmplAstElement ?
-            this.scope.resolve(this.target) :
-            this.scope.resolve(this.host, this.target));
+        this.scope.resolve(this.target) :
+        this.scope.resolve(this.host, this.target);
 
     // The reference is either to an element, an <ng-template> node, or to a directive on an
     // element or template.
@@ -1121,7 +1121,8 @@ class Scope {
 
   /**
    * Look up a `ts.Expression` representing the value of some operation in the current `Scope`,
-   * including any parent scope(s).
+   * including any parent scope(s). This method always returns a mutable clone of the
+   * `ts.Expression` with the comments cleared.
    *
    * @param node a `TmplAstNode` of the operation in question. The lookup performed will depend on
    * the type of this node:
@@ -1142,7 +1143,18 @@ class Scope {
     // Attempt to resolve the operation locally.
     const res = this.resolveLocal(node, directive);
     if (res !== null) {
-      return res;
+      // We want to get a clone of the resolved expression and clear the trailing comments
+      // so they don't continue to appear in every place the expression is used.
+      // As an example, this would otherwise produce:
+      // var _t1 /**T:DIR*/ /*1,2*/ = _ctor1();
+      // _t1 /**T:DIR*/ /*1,2*/.input = 'value';
+      //
+      // In addition, returning a clone prevents the consumer of `Scope#resolve` from
+      // attaching comments at the declaration site.
+
+      const clone = ts.getMutableClone(res);
+      ts.setSyntheticTrailingComments(clone, []);
+      return clone;
     } else if (this.parent !== null) {
       // Check with the parent.
       return this.parent.resolve(node, directive);
@@ -1547,7 +1559,7 @@ class TcbExpressionTranslator {
       return null;
     }
 
-    const expr = ts.getMutableClone(this.scope.resolve(binding));
+    const expr = this.scope.resolve(binding);
     addParseSpanInfo(expr, ast.sourceSpan);
     return expr;
   }
diff --git a/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts b/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts
index ad868292b2..ef4465cca2 100644
--- a/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts
+++ b/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts
@@ -165,6 +165,22 @@ describe('type check blocks diagnostics', () => {
             .toContain('((_t1 /*23,24*/) || (_t1 /*28,29*/) /*23,29*/);');
       });
     });
+
+    describe('attaching comments for generic directive inputs', () => {
+      it('should be correct for directive refs', () => {
+        const DIRECTIVES: TestDeclaration[] = [{
+          type: 'directive',
+          name: 'MyComponent',
+          selector: 'my-cmp',
+          isComponent: true,
+          isGeneric: true,
+          inputs: {'inputA': 'inputA'},
+        }];
+        const TEMPLATE = `<my-cmp [inputA]="''"></my-cmp>`;
+        expect(tcbWithSpans(TEMPLATE, DIRECTIVES))
+            .toContain('_t1.inputA = ("" /*18,20*/) /*8,21*/;');
+      });
+    });
   });
 });