diff --git a/integration/ngcc/test.sh b/integration/ngcc/test.sh
index aea0d8ea53..93448d1db3 100755
--- a/integration/ngcc/test.sh
+++ b/integration/ngcc/test.sh
@@ -104,10 +104,10 @@ assertSucceeded "Expected 'ngcc' to log 'Compiling'."
 
 
 # Did it generate a base factory call for synthesized constructors correctly?
-  grep "const ɵMatTable_BaseFactory = ɵngcc0.ɵɵgetInheritedFactory(MatTable);" node_modules/@angular/material/esm2015/table/table.js
+  grep "const ɵMatTable_BaseFactory = /\*@__PURE__\*/ ɵngcc0.ɵɵgetInheritedFactory(MatTable);" node_modules/@angular/material/esm2015/table/table.js
   assertSucceeded "Expected 'ngcc' to generate a base factory for 'MatTable' in '@angular/material' (esm2015)."
 
-  grep "var ɵMatTable_BaseFactory = ɵngcc0.ɵɵgetInheritedFactory(MatTable);" node_modules/@angular/material/esm5/table/table.js
+  grep "var ɵMatTable_BaseFactory = /\*@__PURE__\*/ ɵngcc0.ɵɵgetInheritedFactory(MatTable);" node_modules/@angular/material/esm5/table/table.js
   assertSucceeded "Expected 'ngcc' to generate a base factory for 'MatTable' in '@angular/material' (esm5)."
 
 
diff --git a/packages/compiler-cli/test/ngtsc/ngtsc_spec.ts b/packages/compiler-cli/test/ngtsc/ngtsc_spec.ts
index 6e6848a80d..886e364fbc 100644
--- a/packages/compiler-cli/test/ngtsc/ngtsc_spec.ts
+++ b/packages/compiler-cli/test/ngtsc/ngtsc_spec.ts
@@ -3822,7 +3822,8 @@ runInEachFileSystem(os => {
 
       expect(jsContents)
           .toContain('function Base_Factory(t) { return new (t || Base)(i0.ɵɵinject(Dep)); }');
-      expect(jsContents).toContain('var \u0275Child_BaseFactory = i0.ɵɵgetInheritedFactory(Child)');
+      expect(jsContents)
+          .toContain('var \u0275Child_BaseFactory = /*@__PURE__*/ i0.ɵɵgetInheritedFactory(Child)');
       expect(jsContents)
           .toContain('function Child_Factory(t) { return \u0275Child_BaseFactory(t || Child); }');
       expect(jsContents)
@@ -3849,7 +3850,8 @@ runInEachFileSystem(os => {
       env.driveMain();
       const jsContents = env.getContents('test.js');
 
-      expect(jsContents).toContain('var \u0275Dir_BaseFactory = i0.ɵɵgetInheritedFactory(Dir)');
+      expect(jsContents)
+          .toContain('var \u0275Dir_BaseFactory = /*@__PURE__*/ i0.ɵɵgetInheritedFactory(Dir)');
     });
 
     it('should wrap "directives" in component metadata in a closure when forward references are present',
diff --git a/packages/compiler/src/output/output_ast.ts b/packages/compiler/src/output/output_ast.ts
index 7a3465447a..dfac81e170 100644
--- a/packages/compiler/src/output/output_ast.ts
+++ b/packages/compiler/src/output/output_ast.ts
@@ -176,8 +176,9 @@ export abstract class Expression {
     return new InvokeMethodExpr(this, name, params, null, sourceSpan);
   }
 
-  callFn(params: Expression[], sourceSpan?: ParseSourceSpan|null): InvokeFunctionExpr {
-    return new InvokeFunctionExpr(this, params, null, sourceSpan);
+  callFn(params: Expression[], sourceSpan?: ParseSourceSpan|null, pure?: boolean):
+      InvokeFunctionExpr {
+    return new InvokeFunctionExpr(this, params, null, sourceSpan, pure);
   }
 
   instantiate(params: Expression[], type?: Type|null, sourceSpan?: ParseSourceSpan|null):
diff --git a/packages/compiler/src/render3/r3_factory.ts b/packages/compiler/src/render3/r3_factory.ts
index fe2f6d2073..c1cb7c923b 100644
--- a/packages/compiler/src/render3/r3_factory.ts
+++ b/packages/compiler/src/render3/r3_factory.ts
@@ -212,7 +212,9 @@ export function compileFactoryFunction(meta: R3FactoryMetadata): R3FactoryFn {
     const baseFactory = o.variable(`ɵ${meta.name}_BaseFactory`);
     const getInheritedFactory = o.importExpr(R3.getInheritedFactory);
     const baseFactoryStmt =
-        baseFactory.set(getInheritedFactory.callFn([meta.internalType]))
+        baseFactory
+            .set(getInheritedFactory.callFn(
+                [meta.internalType], /* sourceSpan */ undefined, /* pure */ true))
             .toDeclStmt(o.INFERRED_TYPE, [o.StmtModifier.Exported, o.StmtModifier.Final]);
     statements.push(baseFactoryStmt);